Nick Mitchell Nick Mitchell founded Ultimate Performance Personal Training in London in 2009 and ran it for fifteen years. He grew it into a premium personal training business with 30 gyms in nine countries across four continents, paid for out of profit, with no franchising, no outside investment and no debt. In 2024 he sold…
Keith Barlow launched Xenom, the "Decathlon of Fitness", in February 2026. Less than eight months later, it is licensed by CrossFit and Hyrox's founders have invested in it.
One newcomer, coming from nowhere, with two of the biggest names in fitness wanting him to win. It may just be the fitness business strategy masterclass of…
Most health trackers on the market start the day by handing you a number. A number that can influence how you feel about yourself and the day ahead. Sleep score. Readiness score. Recovery score. Timothée Manschot, co-founder and CEO of Polsen Health (formerly NOWATCH), doesn’t think a number should get to decide how you feel.…
Thomas Clozel talks quickly. Very quickly. At times his thoughts seem to be generated faster than conversational language can organise them, with a new idea arriving before the previous one has been serialised.
It's a fitting trait for a man who, as CEO and co-founder of the AI biology company Owkin, has spent years trying…
Biological dentistry’s argument about materials has largely been won. The EU banned dental amalgam from January 2025, and the Minamata Convention’s sixth conference agreed a global phase-out by 2034. Ceramic implants entered mainstream consensus in 2023, when the International Team for Implantology put their five-year survival at 97.2%, comparable to titanium. Practitioners treated as cranks…
A biological dentist and a conventional dentist hold the same licence. In the UK both are registered with the General Dental Council, both took the same degree, and neither can practise without the other's qualification. There is no separate register, and no recognised specialty.
What differs is everything downstream: which materials go in the mouth,…
More than an hour after stepping off the main stage at the Health Optimisation Summit in London, Dr Dominik Nischwitz is still talking. The questions that started at the side of the stage followed him up to the gallery balcony, after a steward on a health and safety mission moved everybody on. "I'm not leaving…
“I never thought we would actually get a winner,” says Dr Jamie Justice, Executive Vice President of Health at XPRIZE.
She is talking about XPRIZE Healthspan, the project she oversees. It is a seven-year, $101 million global competition to develop therapies that restore the function people lose as they age.
To win, a team has…
The world’s most private longevity investment conference takes place in Switzerland next month and you are not on the list.
Don’t take it personally. Hardly anyone is.
Between the 14th and the 17th September approximately 140 people will gather in Gstaad for the annual Longevity Investors Conference. One third of them are speakers. The rest…
Updated 10 August 2026. Regulatory status current as of this date.
Most approved peptide medicines are legal when prescribed appropriately. But wellness and lifestyle peptides such as BPC-157, TB-500 and MOTS-c remain unapproved and unproven; the FDA’s July 2026 advisory vote did not make them approved or immediately legal to compound. UK rules depend partly…



