For decades, fasting has been studied as one of the most powerful metabolic interventions affecting health and longevity. In laboratory animals, calorie restriction and fasting can extend lifespan, improve metabolic resilience, and influence cellular repair mechanisms.
The challenge has always been practical: prolonged fasting is difficult to maintain.
The fasting-mimicking diet (FMD) emerged as an…
For eight years, Phil Newman has watched the longevity megatrend gather momentum. As founder and CEO of First Longevity and Editor-in-Chief of Longevity Technology, he has had a front row seat as the industry evolved from niche curiosity to cultural phenomenon. Now he’s building a stage of his own.
The Longevity Show, launching this June…
Hidden dental infections are chronic, low-grade infections in the teeth, surrounding tissues, or jawbone that often produce minimal local symptoms but may contribute to systemic inflammation and ongoing health issues.
They challenge one of the most deeply held assumptions in dentistry: that pain equals problem, and absence of pain equals health.
In many cases, that…
Root canals and autoimmune disease are often linked through theories of chronic inflammation and immune activation, but current scientific evidence does not establish a clear, direct causal relationship.
This is one of the most contested topics in modern dentistry.
Biological dentistry often treats root canal-treated teeth as potential contributors to systemic illness. Conventional dentistry, by…
Gut health firm Viome has announced a partnership with Microsoft to build an AI infrastructure for the human microbiome - a move that could mark the next frontier in personalised health.
At first glance, it sounds like a routine tech deal. In reality, it’s a major step toward programmable biology.
Inside the partnership
Viome’s goal…
McKinsey Health Institute recently released a 59-page report on global metabolic health — and the numbers are impossible to ignore.
Around 900 million adults worldwide are obese, and more than 20 chronic diseases, from diabetes to dementia, are directly linked to obesity. The economic impact is equally severe: $2.76 trillion in GDP could be wiped…
Dental infections can contribute to chronic illness by acting as persistent sources of inflammation, immune activation, and microbial byproducts, although their impact varies depending on the individual, the severity of infection, and overall biological context.
This is one of the most important, and most misunderstood, questions in oral health.
At one extreme, the claim is…
CJC-1295 has one of the strongest published human clinical records of any wellness-market peptide, a Phase 2 trial that was discontinued after a participant death, and a December 2024 FDA advisory committee vote against allowing it into the regulated compounding system. The gap between the science and the regulatory verdict is where its current safety…
Peptide therapy has become a buzzword in high-performance health, with claims ranging from faster recovery and better sleep to improved fat loss, hormonal balance, and even longer lifespan. But while its popularity is growing among athletes, biohackers, and anti-aging enthusiasts, there’s still a lot of confusion around what peptide therapy actually is — and whether…
A root canal is a dental procedure that removes infected or inflamed pulp from inside a tooth, disinfects the canal space, and seals it so the tooth can remain in place.
That is the standard definition. It explains what the procedure does mechanically. It does not settle the harder question, which is whether a root…



