Fasting is one of the longevity movement's favourite rituals but the main reason people give for it does not hold up well in humans.
The promise is autophagy. Skip food for long enough and the body, short of incoming fuel, starts breaking down and recycling its own worn-out parts. That much is real. The catch…
Give a patient a GLP-1 prescription and send them home, and there is a decent chance the drug outlives their commitment to it. Six-month retention runs at around 45 per cent, by the estimate of a company sitting on data from more than 600,000 GLP-1 patients.
Wrap the same drug in a coaching service and…
Marc P. Bernegger started an internet company before the average person was online. He bought Bitcoin at $7. And he walked towards a little-known longevity expert at a conference after the man had said something so radical it caused members of the audience to walk out. That expert was the now-pioneering gerontologist Aubrey de Grey.…
Put a woman and a man in the same room at the same temperature, and the woman's hands, feet and ears will be colder. Not because she's imagining it. Because her body is measurably colder at the surface, and has organised itself that way on purpose.
The short answer to the question the ice-bath industry…
In 2021, Dr Adrijana Kekic, a Mayo Clinic pharmacogenomic specialist with three decades of training in pharmacology and personalised medicine, passed out on her kitchen floor of something preventable that her own physicians, and even her own framework, had missed.
Standard testing had been done within a week of the event. Symptoms had been present.…
YOU(th) raised $4.5m in February. The number is unremarkable. The thinking behind the product is worth a closer look. In late February 2026, the German startup closed a $4.5m round led by Callisto Health, with caesar., adesso Ventures, Antler, Moonstone and 1024 Ventures alongside, plus angel cheques from Jean-Charles Samuelian (Alan, Mistral AI) and Patrick…
Plenty of people have closed their eyes and had one a final throw of the dice in Vegas. Most of them walk away with nothing.
Tonight, Kristian Gkolomeev of Greece is going home with $1.25m after breaking the Men’s 50m Freestyle record, clocking 20.81 in the final event of the night at the inaugural Enhanced…
"If I wanted a doctor's opinion on whether or not people's health is at risk, I would go to a doctor. Not Kieren Perkins."
It takes a lot to push James Magnussen, the three-time Olympic medallist and two-time world champion in the 100m freestyle, out of his naturally relaxed and jovial demeanour. But that’s what…
Longevity has stopped being a Silicon Valley curiosity. Over the past four years, the field has crossed the line from speculative science to institutional industry. Tech billionaires have poured billions into it. Sovereign wealth funds have arrived. The first human trial of partial cellular reprogramming starts this year, with FDA clearance already in hand. A…
During a Zoom call on the 26th January 2024, Aron D'Souza, founder of the Enhanced Games, revealed something to me that he asked me to keep to myself.
The Enhanced Games, which takes place in Las Vegas on Sunday, is the world's first sporting competition in which athletes are permitted to use performance-enhancing substances banned…



