Eli Lilly advances retatrutide to Phase 3 to expand next-generation multi-hormone obesity therapeutics

Eli Lilly is progressing its experimental obesity and type 2 diabetes drug retatrutide into Phase 3 trials, following late-stage data showing significant weight loss and metabolic improvements. Retatrutide belongs to a new class of drugs known as triple agonists, targeting three key metabolic pathways simultaneously. In earlier trials, the drug demonstrated weight loss outcomes exceeding…

March 26, 20260Comments

ByJon Lipsey

HEALTH Explainer

What biological dentistry is and how it connects oral health to systemic disease

Biological dentistry is an approach to oral healthcare that views the teeth, gums, and jaw as part of an interconnected biological system, where dental materials, infections, and procedures can influence systemic health through immune, neurological, and inflammatory pathways. That definition captures a shift that is still under-recognised in mainstream care. Conventional dentistry has historically focused…

March 24, 20260Comments

ByJon Lipsey

HEALTH Explainer

What are AI health assistants and how do they work?

A new category is emerging at the intersection of artificial intelligence, wearable technology, and digital health: the AI health assistant. For years, digital health tools focused on collecting data. Fitness trackers counted steps. Smartwatches measured heart rate. Health apps logged sleep or nutrition. The missing piece was interpretation. AI health assistants aim to fill that…

March 23, 20260Comments

ByJon Lipsey

HEALTH Explainer

Symptoms of hidden dental infections and why they are often missed

Hidden dental infections are chronic, low-grade infections in the teeth, surrounding tissues, or jawbone that often produce minimal local symptoms but may contribute to systemic inflammation and ongoing health issues. They challenge one of the most deeply held assumptions in dentistry: that pain equals problem, and absence of pain equals health. In many cases, that…

March 9, 20260Comments

ByJon Lipsey

HEALTH Explainer

Root canals and autoimmune disease: what the science says

Root canals and autoimmune disease are often linked through theories of chronic inflammation and immune activation, but current scientific evidence does not establish a clear, direct causal relationship. This is one of the most contested topics in modern dentistry. Biological dentistry often treats root canal-treated teeth as potential contributors to systemic illness. Conventional dentistry, by…

February 20, 20260Comments

ByJon Lipsey

HEALTH

The pill made from someone else’s microbiome

Gut health firm Viome has announced a partnership with Microsoft to build an AI infrastructure for the human microbiome - a move that could mark the next frontier in personalised health. At first glance, it sounds like a routine tech deal. In reality, it’s a major step toward programmable biology. Inside the partnership Viome’s goal…

February 6, 20260Comments

ByJon Lipsey

HEALTH Obesity crisis

Metabolic ill health will cost the global economy trillions

McKinsey Health Institute recently released a 59-page report on global metabolic health — and the numbers are impossible to ignore. Around 900 million adults worldwide are obese, and more than 20 chronic diseases, from diabetes to dementia, are directly linked to obesity. The economic impact is equally severe: $2.76 trillion in GDP could be wiped…

February 1, 20260Comments

ByJon Lipsey

HEALTH Explainer

Can dental infections cause chronic illness? What the evidence and biology suggest

Dental infections can contribute to chronic illness by acting as persistent sources of inflammation, immune activation, and microbial byproducts, although their impact varies depending on the individual, the severity of infection, and overall biological context. This is one of the most important, and most misunderstood, questions in oral health. At one extreme, the claim is…

January 20, 20260Comments

ByJon Lipsey

HEALTH Explainer

CJC-1295 Explained: What It Is, How It Works and What You Need to Know

In the world of health optimisation and performance enhancement, CJC-1295 has emerged as a popular peptide among athletes, biohackers, and longevity enthusiasts. It’s often described as a gentler, smarter way to support growth hormone levels — a biological lever tied to muscle recovery, fat metabolism, skin health, and even sleep. But while it’s widely used…

January 19, 20260Comments

ByJon Lipsey

HEALTH Explainer

Peptide Therapy: What It Is, How It Works, and is it Safe or Legal?

Peptide therapy has become a buzzword in high-performance health, with claims ranging from faster recovery and better sleep to improved fat loss, hormonal balance, and even longer lifespan. But while its popularity is growing among athletes, biohackers, and anti-aging enthusiasts, there’s still a lot of confusion around what peptide therapy actually is — and whether…

January 17, 20260Comments

ByJon Lipsey

HEALTH

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