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Fasting-mimicking therapy shows metabolic benefit in clinical trial

A clinical trial examining a fasting-mimicking intervention has reported improvements in several metabolic markers associated with ageing and chronic disease risk, adding to the growing body of research exploring fasting-based nutritional strategies. The study evaluated the metabolic impact of a structured fasting-mimicking protocol designed to simulate many physiological effects of fasting while allowing limited nutrient…

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What is a fasting-mimicking diet and how does it influence metabolic and ageing pathways?

For decades, fasting has been studied as one of the most powerful metabolic interventions affecting health and longevity. In laboratory animals, calorie restriction and fasting can extend lifespan, improve metabolic resilience, and influence cellular repair mechanisms. The challenge has always been practical: prolonged fasting is difficult to maintain. The fasting-mimicking diet (FMD) emerged as an…

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