In 2011, a University of South Florida researcher called Dominic D'Agostino came to Patrick Arnold with a request. He needed a molecule synthesised. The molecule was a ketone ester, a compound that, taken orally, would metabolise in the body into acetoacetate and beta-hydroxybutyric acid, the two endogenous ketones the body produces when it fully metabolises…
The chemist who designed the most consequential undetectable steroid in the history of professional sport spent the last decade of his life trying to build something else. A ketone ester for a Navy-funded research lab. BHB salts. NAD precursors. A longevity formula he was developing with an old partner. A gram of NMN every morning.…



